Title:
Principles of virology / Jane Flint, Department of Molecular Biology, Princeton University, Princeton, New Jersey, Vincent R. Racaniello, Department of Microbiology & Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, Glenn F. Rall, Fox Chase Cancer Center, Philadelphia, Pennsylvania, Theodora Hatziioannou, The Rockefeller University, New York, New York, Anna Marie Skalka, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Author:
Flint, S. Jane, author.
Racaniello, V. R. (Vincent R.), author.
Rall, Glenn F., author.
Hatziioannou, Theodora, author.
Skalka, Anna Marie, author.
American Society for Microbiology.
General Notes:
Includes bibliographical references and index.
Volume 1. Molecular biology -- volume 2. Pathogenesis and control.
Volume 1. Molecular biology. The science of virology ; Foundations ; The infectious cycle ; Molecular biology ; Genomes and genetics ; Structure ; Attachment and entry ; Synthesis of RNA from RNA templates ; Synthesis of RNA from DNA templates ; Processing ; Replication of DNA genomes ; Reverse transcription and integration ; Protein synthesis ; Intracellular trafficking ; Assembly, release, and maturation ; The infected cell ; Appendix : Structure, genome organization, and infectious cycles of viruses featured in this book -- Volume 2. Pathogenesis and control. Infections of populations : history and epidemiology ; Barriers to infection ; The early host response : Cell autonomous and innate immunity ; Adaptive immunity and establishment of memory ; Patterns and pathogenesis ; Cellular transformation and oncogenesis ; Vaccines ; Antiviral drugs ; Therapeutic viruses ; Virus evolution ; Emergence ; Human immunodeficiency virus type I pathogenesis ; Unusual infectious agents ; Appendix : Epidemiology and pathogenesis of selected human viruses.
volume 1. Molecular biology -- volume 2. Pathogenesis and control.
All editions of this textbook have been written according to the authors' philosophy that the best approach to teaching introductory virology is by emphasizing shared principles. Studying the common steps of the viral reproductive cycle illustrated with a set of representative viruses, and considering mechanisms by which these viruses can cause disease, provides an integrated overview of the biology of these infectious agents. Such knowledge cannot be acquired by learning a collection of facts about individual viruses. Consequently, the major goal of this book is to define and illustrate the basic principles of virus biology. In this information-rich age, the quantity of data describing any given virus can be overwhelming, if not indigestible, for student and expert alike. The urge to write more and more about less and less is the curse of reductionist science and the bane of those who write textbooks meant to be used by students. In the fifth edition, the authors continue to distill information with the intent of extracting essential principles, while providing descriptions of how the information was acquired, and tools to encourage readers' exploration of the primary literature. Boxes are used to emphasize major principles and to provide supplementary material of relevance, from explanations of terminology to descriptions of trailblazing experiments. The goal is to illuminate process and strategy as opposed to listing facts and figures. In an effort to make the book readable, the authors have been selective in their choice of viruses that are used as examples. The encyclopedic Fields' Virology (Knipe DM, Howley PM (ed). 2020. Fields Virology, 7th ed. Lippincott Williams & Wilkins, Philadelphia, PA) is recommended as a resource for detailed reviews of specific virus families. --
Publisher:
Wiley ; ASM Press,
Publication Place:
Hoboken, NJ : Washington, DC :
ISBN:
9781683670322
1683670329
9781683672845
1683672844
9781683672852
1683672852
9781683672821
9781683673606
9781683672838
9781683673590
9781683670339
9781683673583
Subject:
Virology.
Viruses.
Microbial genetics.
Viruses
Genetics, Microbial
Molecular Biology
Virology -- methods
Virology
Virologie.
Virus.
G�en�etique microbienne.
Virology.
Virology.
Fulltext.
Internet Resources.
Edition:
Fifth edition.
Contents:
Volume 1. Molecular biology -- volume 2. Pathogenesis and control.
Volume 1. Molecular biology. The science of virology ; Foundations ; The infectious cycle ; Molecular biology ; Genomes and genetics ; Structure ; Attachment and entry ; Synthesis of RNA from RNA templates ; Synthesis of RNA from DNA templates ; Processing ; Replication of DNA genomes ; Reverse transcription and integration ; Protein synthesis ; Intracellular trafficking ; Assembly, release, and maturation ; The infected cell ; Appendix : Structure, genome organization, and infectious cycles of viruses featured in this book -- Volume 2. Pathogenesis and control. Infections of populations : history and epidemiology ; Barriers to infection ; The early host response : Cell autonomous and innate immunity ; Adaptive immunity and establishment of memory ; Patterns and pathogenesis ; Cellular transformation and oncogenesis ; Vaccines ; Antiviral drugs ; Therapeutic viruses ; Virus evolution ; Emergence ; Human immunodeficiency virus type I pathogenesis ; Unusual infectious agents ; Appendix : Epidemiology and pathogenesis of selected human viruses.
volume 1. Molecular biology -- volume 2. Pathogenesis and control.
Physical Description:
2 volumes : illustrations (chiefly color) ;
Publication Date:
[2020]
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