Title:
Clinical Trial Simulations Applications and Trends / edited by Holly H. C. Kimko, Carl C. Peck.
AAPS Advances in the Pharmaceutical Sciences Series,
AAPS Advances in the Pharmaceutical Sciences Series,
Main Entry:
Kimko, Holly H. C.
Peck, Carl C.
SpringerLink (Online service)
Publisher:
Springer New York,
Publication Date:
2011.
Publication Place:
New York, NY :
ISBN:
9781441974150
Subject:
Medicine.
Toxicology.
Biochemistry.
Biomedicine.
Biomedicine general.
Pharmacology/Toxicology.
Biochemistry, general.
Series:
AAPS Advances in the Pharmaceutical Sciences Series, 1
AAPS Advances in the Pharmaceutical Sciences Series, 1
Contents:
Clinical Trial Simulation and Quantitative Pharmacology -- Contribution of Modeling and Simulation Studies in the Regulatory Review: A European Regulatory Perspective -- Contribution of Modeling and Simulation in the Regulatory Review and Decision-Making: U.S FDA Perspective -- Decision-Making in Drug Development: Application of a Model Based Framework for Assessing Trial Performance -- Decision-Making in Drug Development: Application of a Clinical Utility Index -- Adaptive Trial Designs -- Keys of Collaboration to Enhance Efficiency and Impact of Modeling and Simulation -- Leveraging Pharmacometrics in Early Phase Anti-Inflamatory Dug Development -- The Application of Drug-Disease Models in the Development of Anti-Hyperglycemic Agents -- Modeling and Simulation in the Development of Cardiovascular Agents -- Viral Dynamic Modeling and Simulations in HIV and Hepatitis C -- A Model-Based PK/PD Antimicrobial Chemotherapy Drug Development Platform to Simultaneously Combat Infectious Diseases and Drug Resistance -- PKPD and Disease Modeling: Concepts and Applications to Oncology -- Application of Pharmacokinetic-Pharmacodynamic Modeling and Simulation for Erythropoietic Stimulating Agents -- Model Based Development of an Agent for the Treatment of Generalized Anxiety Disorder -- Balancing Efficacy and Safety in the Clinical Development of an Atypical Antipsychotic, Paliperidone Extended-Release -- Application of Modeling and Simulation in the Development of Protein Drugs -- Modeling and Simulation in Pediatric Research and Development -- Disease Progression Analysis: Towards Mechanism-Based Models -- Using a Systems Biology Approach to Explore Hypotheses Underlying Clinical Diversity of the Renin Angiotensin System and the Response to Antihypertensive Therapies -- Recent Developments in Physiologically Based Pharmacokinetic Modeling -- Covariate Distribution Models in Simulation.
Related Records:
Springer eBooks
Printed edition: 9781441974143
Cover Image:
Log in
Help
