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Title: Conjugation and Deconjugation of Ubiquitin Family Modifiers Subcellular Biochemistry / edited by Marcus Groettrup.
Subcellular Biochemistry,
Subcellular biochemistry,

Main Entry: Groettrup, Marcus.
SpringerLink (Online service)

Publisher: Springer New York,
Publication Date: 2010.
Publication Place: New York, NY :
ISBN: 9781441966766
Subject: Medicine.
Biomedicine.
Molecular Medicine.

Series: Subcellular Biochemistry, 54
Subcellular biochemistry, 54

Contents: Preface: New Paradigms in the Conjugation of Ubiquitin Family Modifiers -- Activation of Ubiquitin and Ubiquitin‑Like Proteins -- Control of Ubiquitin Conjugation by Cdc48 and Its Cofactors -- Regulation of Ubiquitin Receptors by Coupled Monoubiquitination -- Control of Cullin‑Ring Ubiquitin Ligase Activity by Nedd8 -- Control of Deneddylation by the Cop9 Signalosome -- Mechanism, Specificity and Structure of the Deubiquitinases -- Ubiquitin Conjugation and Deconjugation in NF‑kB Signaling -- Functions of Linear Ubiquitin Chains in the NF‑kB Pathway: Linear Polyubiquitin in NF‑κB Signaling -- Assembly of K11‑Linked Ubiquitin Chains by the Anaphase‑Promoting Complex -- Ubiquitin Family Members in the Regulation of the Tumor Suppressor p53 -- Ubiquitylation in the ERAD Pathway -- Pupylation: A Signal for Proteasomal Degradation in Mycobacterium tuberculosis -- sumo Control -- The In Vivo Functions of Desumoylating Enzymes -- Regulatory Functions of Ubiquitin and Sumo in DNA Repair Pathways -- Sumoylation as a Signal for Polyubiquitylation and Proteasomal Degradation -- In Vivo Functions of Isgylation -- Identification and Validation of ISG15 Target Proteins -- FAT 10: Activated by UBA6 and Functioning in Protein Degradation.
Related Records: Springer eBooks
Printed edition: 9781441966759

Cover Image: http://images.amazon.com/images/P/9781441966766.jpg

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